Pan Cytokeratin AE1/AE3 0,5mL
Specificity and Comments:
AE1/AE3 recognizes the acidic and basic (Type I and II) subfamilies of cytokeratins. The cocktail of these two antibodies can be used to detect most human epithelia. The acidic cytokeratins have molecular weights of 56.5, 55, 51, 50, 50, 48 46, 45, and 40 kDa. The basic cytokeratins have molecular weights of 65-67, 64, 59, 58, 56 and 52 kDa. This pan cytokeratin antibody has proved useful as a screener for the majority of human carcinomas.
Species Reactivity:
Human, dog, fish, mouse, rat, rabbit, bovine and chicken
Clone: AE1/AE3
Isotype: IgG1
Immunogen: Human epidermal cytokeratins
Hybridoma:
Produced by the fusion between BALB/c splenocytes and mouse myeloma P3 cells.
Known Applications: Immunohistochemistry (formalin-fixed-paraffin embedded tissues)
Positive Control: Skin or adenocarcinoma
Cellular Localization: Cytoplasmic
Supplied As:
Buffer with protein carrier and preservative
Storage and Stability:
Store vial at 4°C. Stable for 18 months.