This antibody reacts with human GFAP and has been solid phase
absorbed with human and cow serum. Anti-GFAP stains astrocytes and some groups
of ependymal cells and their corresponding tumors. In the peripheral nervous
system, Schwann cells, enteric glial cells and satellite cells are stained. Weak
staining of axons has been observed which is caused by cross-reaction with
neurofilament. It is useful for distinguishing neoplasms of astrocytic origin
from other neoplasms in the central nervous system. Negative staining has been
observed with lymphatic tissue, muscle, gastrointestinal tract, liver, kidney,
pancreas and bladder.