CD57 (Natural Killer Cell) 1,0mL
Specificity and Comments:
Recognizes a 110kDa protein on human lymphocyte cell surface that is identified as CD57. NK-1 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. NK-1 reportedly also reacts with a variety of cell types in non-lymphoid tissues. NK-1 stains neuroendocrine cells and their respective tumors.
Species Reactivity:
Human, Cat, Rat, Mouse, Hamster, Chicken, Quail,
Fish, Xenopus, Leech, Insect and Drosophila.
Clone: NK1
Isotype: IgM/?
Immunogen:
Human peripheral blood mononuclear cells
Hybridoma:
Produced by the fusion between BALB/c splenocytes
and mouse myeloma p3-NS-1/Ag4-1(NS1) cells
Known Applications: Immunohistochemistry (formalin-fixed/paraffin-embedded)
Positive Control:
Large granular lymphocytes (NK cells) in tonsil
Cellular Localization:
Cell membrane in germinal centers of lymph nodes or tonsils
Supplied As:
Buffer with protein carrier and preservative
Storage and Stability:
Store at 4°C. Stable for 18 months.