CMV is a member of the human herpes virus-5, HHV-5
group and can be transmitted via breast milk, during organ transplantation,
sexual activity or blood transfusions. It is estimated that 40-100% of people
may be infected with this virus (1,2,4). CMV infections are common causes of
morbidity and mortality especially in immune compromised individuals (1-3). The
in situ hybridization technique offers an important advantage over
immunohistochemistry, as it virtually lacks background, and allows a clean and
sharp viewing of the histological preparation.