Pronase
(Streptomyces griseus) is a commonly used digestive enzyme. In formalin-fixed
paraffin-embedded tissues, certain antibody protocols require enzyme
pretreatment for proper immunohistochemical staining.
CAREZYME
III is an aggressive enzyme and can be used at room temperature or at 37°C.
Certain
antibodies such as EGFR require this type of aggressive enzyme digestion.
This
product is provided as a two component system and can be used at different
concentrations.
CAREZYME
III is not compatible with antibodies AE1/AE3 or AE3. It can also be used on an
automated staining system.