Pan Cytokeratin AE1/AE3 1,0 mL

Specificity and Comments:

AE1/AE3 recognizes the acidic and basic (Type I and II) subfamilies of cytokeratins. The cocktail of these two antibodies can be used to detect most human epithelia. The acidic cytokeratins have molecular weights of 56.5, 55, 51, 50, 50, 48 46, 45, and 40 kDa. The basic cytokeratins have molecular weights of 65-67, 64, 59, 58, 56 and 52 kDa. This pan cytokeratin antibody has proved useful as a screener for the majority of human carcinomas.

 

 

Species Reactivity:

Human, dog, fish, mouse, rat, rabbit, bovine and chicken

 

Clone: AE1/AE3

 

Isotype: IgG1

 

Immunogen: Human epidermal cytokeratins

 

Hybridoma:

Produced by the fusion between BALB/c splenocytes and mouse myeloma P3 cells.

Known Applications: Immunohistochemistry (formalin-fixed-paraffin embedded tissues)

 

Positive Control: Skin or adenocarcinoma

Cellular Localization: Cytoplasmic

 

Supplied As:

Buffer with protein carrier and preservative

 

Storage and Stability:

Store vial at 4°C. Stable for 18 months.