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Kappa (M) + Lambda (P) [L1C1 + Polyclonal] 6.0 mL

BC-API3159DSAA
Produktfråga

Vad vill du veta om Kappa (M) + Lambda (P) [L1C1 + Polyclonal] 6.0 mL?

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Beskrivning

Kappa (M) + Lambda (P)

Kappa and Lambda antibodies are usually run together on two separate tissues. In normal tissue, the Kappa and Lambda cell ratio is approximately 2:1. The double stain antibody allows the investigator to simultaneously see both Kappa (M) (brown) and Lambda (P) (red) on the same tissue section, thus allowing the end-user a more accurate and easier assessment of both stains.

The antibody cocktail recognizes both Kappa and Lambda light chains. It is reportedly useful in the identification of myelomas, plasmacytomas, and certain non-Hodgkin’s lymphomas. The most common feature of these malignancies is the restricted expression of a single light chain class. Demonstration of clonality in lymphoid infiltrates may indicate that the infiltrate is malignant.

 

INTENDED USE

IVD

FORMAT

Predilute

VOLUME

6.0 ml

SOURCE

Mouse Monoclonal, Rabbit Polyclonal

CLONE

N/A, L1C1

ISOTYPE

IgG, IgG1

ANTIGEN

Kappa light chain, Lambda Light Chain

LOCALIZATION

Cytoplasmic

POSITIVE CONTROL

Tonsil or bone marrow

SPECIES REACTIVITY

Human; others not tested

 

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