D2-40 (Lymphatic Marker) 0,5 mL
Specificity and Comments: D2-40 reacts with an O-linked sialoiglycoportein (MW 40K) found on lymphatic endothelium, fetal testis and on the surface of germ-cell tumors. D2-40is also a new selective marker of lymphatic endothelium in normal tissues and vascular lesions. In recent studies, clone De-40 has shown staining reaction in lymphatic channel endothelium, but not in the adjacent capillary. Proliferation and distribution of lymphatic vessels may also be related to prognosis and early metastasis.
Species Reactivity: Human, others not tested.
Applications: Formalin-fixed paraffin-embedded tissues
Positive Controls: Breast cancer, Most tumors
Cellular Localizations: Lymphatic endothelium
Pretreatment Required: None
Recommended Dilution: 1:50-100
Diluent: Da Vinci Green
Intended Use: For Research Use Only