Produkten har lagts i din varukorg Visa varukorgenTill kassan
Din webbläsare stöds ej. För bästa upplevelsen rekommenderas en nyare version eller en annan webbläsare.
För att ge dig bättre service använder vi cookies. Genom att fortsätta på sidan godkänner du vår användning av cookies.

CDH17 (M) 0,1 ml

BC-ACI3111A
Produktfråga

Vad vill du veta om CDH17 (M) 0,1 ml?

Skicka

Beskrivning

CDH17 (M)

CDH17 antibody (Cadherin 17 or LI-cadherin) is a novel oncogene which is involved in tumor invasion and metastasis and is expressed in intestinal epithelium (1,2). CDH17 is a highly specific marker in colon cancer (99/99, 100%) and is a more sensitive marker than CDX2 (93/99, 94%) and CK20 (91/99, 92%) (3). Overexpression of CDH17 (and conversely, underexpression of CDX2) correlates to poor prognosis in patients with epithelial ovarian cancer (1). CDH17 may be helpful for early diagnosis of Barrett’s esophagus (4). CDH17 has been shown to be a useful marker for distinguishing between primary urinary bladder adenocarcinoma and urothelial carcinoma with glandular differentiation (5). Note that it does not distinguish primary urinary bladder adenocarcinoma from colorectal adenocarcinoma secondarily involving the bladder (5).

 

WEIGHT .4 lbs
DIMENSIONS 1 x 1 x 1 in
INTENDED USE

IVD

SOURCE

Mouse Monoclonal

CLONE

1H3

ISOTYPE

IgG1/kappa

ANTIGEN

CDH17

LOCALIZATION

Cytoplasmic and cell membrane

POSITIVE CONTROL

Colon Carcinoma

 

Läs mer ...Stäng