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CD8 Clone: c8/144B 0,1 ml

BC-ACI3160A
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Beskrivning

CD8 [C8/144B]

The CD8 antibody reacts with the 32 kDa CD8 protein. CD8 stains cells with cytotoxic activity, including cortical thymocytes, cytotoxic/suppressor T-cells and a subset of natural killer cells. CD4 and CD8 positive and negative staining are indicative of T-cell neoplasms (1-2). CD4 and CD8 may also be used to differentiate between mycosis fungoides and cutaneous inflammatory processes (3-4). CD8 can be used in panels with CD4, CD56, TIA-1 to aid in identifying subsets of inflammatory skin diseases (5). Recently, CD8 has been used in panels with CD103, FOXP3, and PD-l for the identification of CD8+ tumor infiltrating lymphocytes and their potential value for immune therapy (6-8).

 

INTENDED USE

IVD

FORMAT

Concentrate, Predilute

VOLUME

0.1 ml, 1.0 ml, 6.0 ml

SOURCE

Mouse Monoclonal

CLONE

C8/144B

ISOTYPE

IgG1/kappa

ANTIGEN

CD8

LOCALIZATION

Cell surface

POSITIVE CONTROL

Tonsil and normal Colon

 

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