Mouse primary antibodies on rat tissues are
advantageous because mouse secondary detection systems can be used with minimum
cross-reactivity to endogenous rat IgG.
Biocare Medical has developed a Mouse-on-Rat
horseradish peroxidase (HRP) polymer detection system with minimal
cross-reactivity to rat tissues. It can be used with formalin-fixed
paraffin-embedded tissues, floating sections, frozen sections and cell culture
preparations. Biocare Medical has novel products to help eliminate persistent
rat IgG. XR Factor is a very potent blocker for eliminating endogenous rat IgG.
By adding 1-2 drops (1 drop equals 33 µl) of the XR Factor to 2.5 ml of the
Mouse-on-Rat Polymer, endogenous rat IgG will be dramatically reduced and/or
completely eliminated.
Available as a bundle containing detection
polymer, blocking and HIER solution or available
individually.
Supplied as: HRP Micro-polymer.