| INTENDED USE |
IVD |
| SPECIES REACTIVITY |
Human |
| SOURCE |
Mouse Monoclonal |
| CLONE |
27G12 |
| ISOTYPE |
IgG1 |
| ANTIGEN |
Synaptophysin |
| LOCALIZATION |
Cytoplasmic |
| POSITIVE CONTROL |
Pancreas, colon, small cell lung
carcinoma |
This monoclonal antibody [clone 27G12] is a reliable marker for
neuroendocrine and neuronal neoplasms, as well as their normal counterparts.
Synaptophysin has a higher degree of specificity than NSE, but is often used in
conjunction with CD56, NSE and chromogranin. This new clone is very specific and
provides sharper staining when compared to other rabbit synaptophysin
antibodies. In-house studies, reference laboratories, European institutions and
NordiQC have validated this antibody as a first line screener for neuroendocrine
tumors.