| Specifications |
|
|
| Intended Use
|
IVD |
| Source |
Human |
| Species
Reactivity
|
Rabbit
Monoclonal |
| Clone |
SP15 |
| Isotype |
lgG |
| Antigen |
Placental
Alkaline Phosphatase (PLAP) |
| Cellular
Localization
|
Cell
Membrane |
| Positive
Control
|
Placenta or
seminoma |
|
|
|
|
|
Rabbit monoclonal (PLAP) reacts with a
membrane-bound isoenzyme (Regan and Nagao type) of Placental Alkaline
Phosphatase occurring in the placenta during the 3rd trimester of gestation.
This antibody is highly specific to PLAP and shows no crossreaction with other
isoenzymes of alkaline phosphatases. It is useful in the identification of
testicular germ cell tumors. Unlike germ cell tumors, PLAP-positive somatic cell
tumors uniformly express epithelial membrane antigen
(EMA).