Specifications |
|
Intended Use |
IVD |
Source |
Human |
Species Reactivity |
Rabbit Monoclonal |
Clone |
SP15 |
Isotype |
lgG |
Antigen |
Placental Alkaline Phosphatase (PLAP) |
Cellular Localization |
Cell Membrane |
Positive Control |
Placenta or seminoma |
|
|
|
Rabbit monoclonal (PLAP) reacts with a membrane-bound isoenzyme
(Regan and Nagao type) of Placental Alkaline Phosphatase occurring in the
placenta during the 3rd trimester of gestation. This antibody is highly specific
to PLAP and shows no crossreaction with other isoenzymes of alkaline
phosphatases. It is useful in the identification of testicular germ cell tumors.
Unlike germ cell tumors, PLAP-positive somatic cell tumors uniformly express
epithelial membrane antigen (EMA).