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Prostate stained with HMW Cytokeratin antibody

Cytokeratin HMW (34BE12) 0,1 mL

BC-CM127A
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SPECIES REACTIVITY

Human

SOURCE

Mouse Monoclonal

CLONE

34ßE12

ISOTYPE

IgG1/kappa

ANTIGEN

HMW CK [34ßE12]

LOCALIZATION

Cytoplasmic

POSITIVE CONTROL

Skin, prostate or squamous cell carcinoma

Cytokeratin HMW [34ßE12] antibody recognizes Cytokeratins 1, 5, 10 and 14. This antibody is expressed in squamous and adenosquamous carcinomas and is negative in adenocarcinomas. In normal epithelia, [34ßE12] stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. It is also expressed in ductal and squamous epithelium over a wide range of organ tissues. Studies have shown that [34ßE12] is useful as a differential marker for squamous carcinomas and adenocarcinomas as well as for benign and malignant tumors of the prostate gland.

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