CD57 (Natural Killer Cell) 1,0mL

Specificity and Comments:

Recognizes a 110kDa protein on human lymphocyte cell surface that is identified as CD57. NK-1 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. NK-1 reportedly also reacts with a variety of cell types in non-lymphoid tissues. NK-1 stains neuroendocrine cells and their respective tumors.

 

 

Species Reactivity:

Human, Cat, Rat, Mouse, Hamster, Chicken, Quail,

Fish, Xenopus, Leech, Insect and Drosophila.

 

Clone: NK1

 

Isotype: IgM/?

 

Immunogen:

Human peripheral blood mononuclear cells

 

Hybridoma:

Produced by the fusion between BALB/c splenocytes

and mouse myeloma p3-NS-1/Ag4-1(NS1) cells

 

Known Applications: Immunohistochemistry (formalin-fixed/paraffin-embedded)

 

Positive Control:

Large granular lymphocytes (NK cells) in tonsil

Cellular Localization:

Cell membrane in germinal centers of lymph nodes or tonsils

 

Supplied As:

Buffer with protein carrier and preservative

 

Storage and Stability:

Store at 4°C. Stable for 18 months.