CD45RO (UCHL-1) 0,5mL

Specificity and Comments:

CD45RO recognizes a 180kDa protein, identified as isoform of leukocyte common antigen (CD45RO) (4th Leukocyte Typing Workshop: Code No. N31). UCHL-1 reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. UCHL-1 shows no reactivity with normal B-cells or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, UCHL-1 is useful for the identification of normal T-cells and T-cell lymphomas.

 

 

Species Reactivity: Human; others not tested.

 

Clone: UCHL-1

 

Isotype: IgG2a/?

 

Immunogen:

Interleukin-2-dependent human T lymphocytes

 

Known Applications: Immunohistochemistry

(formalin-fixed paraffin-embedded tissues)

 

 

Positive Control: T-cell lymphoma or tonsil

Cellular Localization: Cell membrane

 

Supplied As:

Buffer with protein carrier and preservative

 

Storage and Stability:

Store at 4°C. Antibody is stable for 18 months.