CD34 (QBEnd/10) 0,5mL

 

Specificity and Comments:

CD34 recognizes a single chain transmembrane glycoprotein of 110kDa, which is identified as CD34. This antigen is selectively expressed on human lymphoid and myeloid hematopoietic progenitor cells. The antibody to CD34 also reacts with vascular endothelial cells in normal tissues, and in benign and malignant proliferations. The utility of CD34 has value in the studies of benign and malignant vacular tumors as will as characterization of acute leukemia in bone marrow. CD34 has been used to measure angiogenesis in many types of tumors, which reportedly predicts tumor recurrence. It is also used to differentiate dermatofibrosarcoma protuberans from fibrous histiocytoma.

 

 

Species Reactivity: Human; others not tested.

 

Clone: QBEnd/10

Isotype: IgG1

 

Immunogen:

Detergent solubilized vesicular suspension prepared for a perfusate of human term placenta.

 

Known Applications: Immunohistochemistry

(formalin-fixed paraffin-embedded tissues)

Positive Control: Skin, tonsil or angiosarcoma

 

Supplied As:

Buffer with protein carrier and preservative

 

Storage and Stability:

Store vial at 4°C. Stable for 18 months.