CD23 (1B12) 1,0mL

Specificity and Comments:

CD23 is a 45kDa glycoprotein that acts as a receptor for IgE. It is expressed by interleukin-4 activated B-lymphocytes and also by activated macrophages and a proportion of follicular dentritic cells. CD23 has been shown to be useful for the differentiation of small lymphocytic lymphomas and mantle cell lymphoma.

 

Species Reactivity:

Human; others not tested.

 

Clone: 1B12

 

Isotype: IgG1

 

Known Applications: Immunohistochemistry (formalin-fixed paraffin-embedded tissues)

 

 

Positive Control:

Follicular lymphoma or tonsil (mantle cell lymphomas are negative)

 

Cellular Localization: Cytoplasmic/membrane

 

Supplied As:

Buffer with protein carrier and preservative

 

Storage and Stability:

Store at 4°C. Antibody is stable for 18 mont