CD10 (CALLA) 0,5mL
Specificity and Comments
Human CD10, also known as common acute lymphoblastic leukemia (CALLA), has been shown to react with TdT+ lymphoblastic leukemia, follicular germinal cell lymphoma, Burkitt’s lymphoma, and chronic myelocytic leukemia. CD10 also marks normal early lymphoid progenitor cells, immature B-cells in adult bone marrow, and germinal cells in normal tonsil and/or normal lymphoid tissue. It is also expressed in some non-lymphoid tissues such as fibroblasts, breast myoepithelium, and brush border of kidney. Recently, CD10 has been used in a panel for mantle cell lymphoma with cyclin D1(+), CD43 (+), CD5 (+), IgM (+), CD23 (?) and CD10 (?).
Species Reactivity: Human; others not tested.
Clone: 56C6
Isotype: IgG1
Immunogen:
Prokaryotic recombinant fusion protein corresponding to the external of the CD10 glycoprotein
Known Applications: Immnohistochemistry
(formalin-fixed paraffin-embedded tissues)
Cellular Location: Cell membrane
Control Tissue:
Tonsil, kidney, lymphoblastic leukemia
Supplied As:
Buffer with protein carrier and preservative
*Includes Renoir Red Diluent (PD904JJ)
and BORGDECLOAKER (BD1000MM)
**Includes Renoir Red Diluent (PD904H)
and BORGDECLOAKER (BD1000S-250)
Storage and Stability:
Store vial at 4°C. Stable for 18 months