p53 Tumor Suppressor Protein 1,0 mL
Specificity and Comments:
Recognizes a 53kDa phosphoprotein, identified as p53 suppressor gene product. It reacts with mutant as well as wild form of p53. Its epitope maps within the N-terminus (aa 37-45) of p53. P53 has been demonstrated in many kinds of tumors including breast colon and prostate.
Species Reactivity: Human, monkey & cow
Clone: DO7
Isotype: IgG2b /?
Immunogen:
Recombinant human wild type p53 protein
expressed in E. coli
Hybridoma:
Produced by the fusion between mouse splenocytes and mouse myeloma X63 Ag8-653 cells
Known Applications: Immunohistochemistry (formalin–fixed paraffin-embedded tissues)
Positive Control: Breast or colon cancer
Cellular Localization: Nuclear
Supplied As:
Buffer with protein carrier and preservative
Storage and Stability:
Store vial at 4°C. Stable for 18 months.