CDX2 1,0 mL
Specificity and Comments:
CDX2 is a homeobox gene that encodes an intestine-specific transcription
factor. It is expressed in the nuclei of epithelial cells throughout the
intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and
metastatic colorectal carcinomas and has also been demonstrated in the
intestinal metaplasia of the stomach and intestinal-type gastric cancer, while
it is not expressed in the normal gastric mucosa. Studies have shown that CDX2
is superior marker compared to CK20.
Species Reactivity: Human; other not tested.
Clone: CDX2-88
Isotype: IgG1
Immunogen: Full-length CDX2 recombinant protein
Known Applications: Immunohistochemistry (formalin-fixed paraffin-embedded
tissues)
Positive Control: Colon cancer
Cellular Localization: Nuclear
Supplied As: Buffer with protein carrier and preservative
Storage and Stability: Store vial at 4°C. Stable for 18
months.