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Pan Melanoma + Ki-67 25 ml

BC-PM362DSH
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Description

Specifications  
Intended Use
Source , 
Species Reactivity , 
Clone
Isotype
Antigen
Cellular Localization , 
Positive Control
Normal Tissue
Abnormal Tissue
This Multiplex application serves as a tool to identify the proliferation rate of melanocytic lesions in cases in which melanocytes are sparse; there are dense lymphocytic infiltrates; and melanocytes are admixed with fibroblasts. In general, a higher proliferative fraction is seen in melanoma than in melanocytic nevi. There are many types of nevi, and some simulate melanoma closely. If the Multiplex stain shows a very low Ki-67 (DAB) labeling rate in MART-1/Tyrosinase positive cells (Fast Red), this favors benignity. A high rate, especially toward the deep part of a melanocytic lesion raises the possibility of malignancy.
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