Vimentin 1,0 mL

Specificity and Comments:

Recognizes a 57-60kDa protein, which is identified as vimentin. It shows no cross-reactivity with other closely related intermediate filament proteins such as desmin and GFAP. Vimentin is the main intermediate filament protein in mesenchymal cells, and therefore is of value in the differential diagnosis of undifferentiated neoplasms including melanoma and sarcoma. Vimentin can also serve as an internal control for formalin-fixed tissues that are over-fixed.

 

 

Species Reactivity:

This antibody has broad species reactivity including: human, monkey, cow, horse, pig, rabbit, dog, cat, rat, mouse, hamster, gerbil and chicken.

 

Clone: V9

 

Isotype: IgG1 / ?

 

Immunogen:

Purified vimentin from pig eye lens

 

Known Applications: Immunohistochemistry (formalin-fixed paraffin-embedded tissues)

 

Control Tissue: Melanoma

 

Cellular Localization: Variable

 

Supplied As:

Buffer with carrier protein and preservative

 

Storage and Stability:

Store vial at 4°C. Antibody is stable for 18 months.