The product has been added to your shopping cart Show shopping cartCheckout
Your browser is not supported. For the best experience, a newer version or another browser is recommended.
In order to give you better service we use cookies. By continuing to browse the site you are agreeing to our use of cookies.
Breast cancer stained with E-cadherin

E-cadherin 1,0 mL

BC-CM170C
Not in stock
Product question

What would you like to know about E-cadherin 1,0 mL?

Send

Description

E-cadherin 1,0 mL
Specificity and Comments:
E-cadherin is a transmembrane glycoprotein that mediates epithelial cell-to-cell adhesion. The loss of E-cadherin can result in the disruption of cell clusters. It is therefore, postulated that E-cadherin may function as a tumor suppressor protein. The loss of E-cadherin has been associtated with metastasis and poor prognosis in invasive breast cancer and can help differentiate between ductal and lobular neoplasms of the breast. It has also been shown to be an independent predictor in the disease progression in bladder cancer.
Species Reactivity: Human; other not tested.
Clone: HECD-1
Isotype: IgG1
Immunogen: Breast tumor cell line MCF-7
Known Applications: Immunohistochemistry (formalin-fixed paraffin-embedded tissues).
Positive Control: Breast cancer
Cellular Localization: Cytoplasmic/membrane
Supplied As:
Buffer with protein carrier and preservative
Storage and Stability:
Store at 4°C. Antibody is stable for 18 months.
More ...Close