The product has been added to your shopping cart Show shopping cartCheckout
Your browser is not supported. For the best experience, a newer version or another browser is recommended.
In order to give you better service we use cookies. By continuing to browse the site you are agreeing to our use of cookies.
Colon cancer stained with Caspase-3 antibody

Caspase- 3 (cleaved) (p) 0,1 mL

BC-CP229A
Not in stock
Product question

What would you like to know about Caspase- 3 (cleaved) (p) 0,1 mL?

Send

Description

Specifications  
Intended Use
Source
Species Reactivity , 
Clone
Isotype
Antigen
Cellular Localization
Positive Control , 
Normal Tissue , 
Abnormal Tissue , 
Apoptosis is a process, in which cells activate an intrinsic suicide mechanism that destroys themselves. The proteases that mediate this execution are called caspases (cysteinyl-aspartic acid proteases). Apoptosis has gained central importance in the study of many biological processes, including neoplasia, neurodegenerative diseases, and development. Cleaved caspase-3 detects endogenous levels of the large fragment (17/19 kDa) of activated caspase-3 resulting from cleavage adjacent to (Asp175). Activation of caspase-3 requires proteolytic processing of its inactive zymogen into actived p17 and p12 subunits. Cleavage of caspase-3 requires aspartic acid at the P1 position. This antibody does not cross-react with other cleaved caspases.
More ...Close