Calponin 1,0 mL

Specificity and Comments:

Calponin (34 Kd polypeptide) is a cytoskeleton-associated actin-binding protein that also interacts tropomyosin and calmodulin. Calponin has been found to be useful as a marker for myoepithelial and basal lamina in differentiating microinvasive from in situ ductal carcinomas of the breast. Calponin has also been useful in malignant myoepithelium and pleomorphoric adenoma of salivary gland as well as a useful marker for fine needle aspirates of papillary breast lesions.

Species Reactivity:

Human and rat; others not tested.

Clone: CALP

Isotypes: IgG1, kappa

Immunogen: Crude human uterus extract

Known Applications: Immunohistochemistry (formalin-fixed paraffin-embedded)

Positive Control:

Myoepithelium in normal breast glands

Cellular Localization: Cytoplasmic

Supplied As:

Buffer with protein carrier and preservative

Storage and Stability:

Store vial at 4°C. Stable for 18 months