CD10 (CALLA) 1,0mL

Specificity and Comments

Human CD10, also known as common acute lymphoblastic leukemia (CALLA), has been shown to react with TdT+ lymphoblastic leukemia, follicular germinal cell lymphoma, Burkitt’s lymphoma, and chronic myelocytic leukemia. CD10 also marks normal early lymphoid progenitor cells, immature B-cells in adult bone marrow, and germinal cells in normal tonsil and/or normal lymphoid tissue. It is also expressed in some non-lymphoid tissues such as fibroblasts, breast myoepithelium, and brush border of kidney. Recently, CD10 has been used in a panel for mantle cell lymphoma with cyclin D1(+), CD43 (+), CD5 (+), IgM (+), CD23 (?) and CD10 (?).

 

 

Species Reactivity: Human; others not tested.

 

Clone: 56C6

 

Isotype: IgG1

 

Immunogen:

Prokaryotic recombinant fusion protein corresponding to the external of the CD10 glycoprotein

 

Known Applications: Immnohistochemistry

(formalin-fixed paraffin-embedded tissues)

Cellular Location: Cell membrane

 

Control Tissue:

Tonsil, kidney, lymphoblastic leukemia

 

Supplied As:

Buffer with protein carrier and preservative

*Includes Renoir Red Diluent (PD904JJ)

and BORGDECLOAKER (BD1000MM)

**Includes Renoir Red Diluent (PD904H)

and BORGDECLOAKER (BD1000S-250)

 

Storage and Stability:

Store vial at 4°C. Stable for 18 months