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Residual CD23 positivity in mantle cell lymphoma

CD23 (1B12) 1,0mL

BC-CM100C
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Description

CD23 (1B12) 1,0mL
Specificity and Comments:
CD23 is a 45kDa glycoprotein that acts as a receptor for IgE. It is expressed by interleukin-4 activated B-lymphocytes and also by activated macrophages and a proportion of follicular dentritic cells. CD23 has been shown to be useful for the differentiation of small lymphocytic lymphomas and mantle cell lymphoma.
 
Species Reactivity:
Human; others not tested.
 
Clone: 1B12
 
Isotype: IgG1
 
Known Applications: Immunohistochemistry (formalin-fixed paraffin-embedded tissues)
 
 
Positive Control:
Follicular lymphoma or tonsil (mantle cell lymphomas are negative)
 
Cellular Localization: Cytoplasmic/membrane
 
Supplied As:
Buffer with protein carrier and preservative
 
Storage and Stability:
Store at 4°C. Antibody is stable for 18 mont
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