Myogenin 0,1 mL

Specificity and Comments:

Myogenin is a member of a family of myogenic genes that also includes MyoD. These genes encode a set of transcription factors that are essential for muscle development. Expression of myogenin is restricted to cells of skeletal muscle origin. Clone MG007 has been shown to label human myogenin and label neonatal mouse, rat and cat tissues. Staining has also been found in myoblasts from human fetal limbs. No reactivity was found in adult skeletal muscle. Myogenin has been observed to stain the vast majority of rhabdomyosarcomas and Wilm’s tumors. No activity was observed in Ewing’s sarcoma/peripheral primitive neuroectodermal tumor, or in neuroblastomas.

 

Species Reactivity: Human, mouse, rat and cat

 

Clone: MyG007

 

Isotype: IgG1, kappa

 

Immunogen: Myogenin peptide

 

Known Applications: Immunohistochemistry (formalin-fixed paraffin-embedded tissues)

 

 

Positive Control: Rhabdomyosarcoma

 

Cellular Localization: Nuclear

 

Supplied As:

Buffer with protein carrier and preservative

*Includes Van Gogh Yellow Diluent (PD902JJ)

***Includes Van Gogh Yellow Diluent (PD902H)

 

Storage and Stability:

Store vial at 4°C. Stable for 18 months.