CDX2 0,5 mL

Specificity and Comments:

CDX2 is a homeobox gene that encodes an intestine-specific transcription factor. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.

Species Reactivity: Human; other not tested.

Clone: CDX2-88

Isotype: IgG1

Immunogen:

Full-length CDX2 recombinant protein

Known Applications: Immunohistochemistry (formalin-fixed paraffin-embedded tissues)

Positive Control: Colon cancer

Cellular Localization: Nuclear

Supplied As:

Buffer with protein carrier and preservative

Storage and Stability:

Store vial at 4°C. Stable for 18 months.